Other useful agents of the present invention may include digestive agents, such as sulfasalazine commercially available as azulfidine , rabeprazole sodium commercially available as aciphex , lubiprostone commercially available as amitiza , dicyclomine hydrochloride commercially available as bentyl , sucralfate commercially available as carafate , lactulose commercially available as chronulac , docusate commercially available as colace , balsalazide disodium commercially available as colazal , losartan potassium commercially available as cozaar , olsalazine sodium commercially available as dipentum , chlordiazepoxide hydrochloride, clidinium bromide commercially available as librax , esomeprazole magnesium commercially available as nexium , famotidine commercially available as pepcid , lansoprazole commercially available as prevacid , lansoprazole and naproxen commercially available as prevacid naprapac ,.
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in a multiple dose study of 12 patients with mild to moderate hepatic impairment administered 20 mg aciphex delayed-release tablets once daily for eight days, auc 0- and c max values increased approximately 20 compared to values in healthy age- and gender-matched subjects.
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the median inhibitory effect of aciphex on 24 hour gastric acidity is 88 of maximal after the first dose.
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